GeroNova Research R-Lipoic Acid 300mg 120 Caps - Stabilized R-Alpha Lipoic Acid With Superior Bioavailability, Metabolic Activity & Healthy Aging Support - Gluten Free & Non-GMO Antioxidant Supplement

I bought this product directly from Geronova for several years after first having taken Alpha Lipoic Acid. It was immediately apparent that the Geronova R-Lipoic Acid is much more potent for equivalent milligrams. It has helped to reduce my migraines more than anything else I have tried. It was recommended by a headache specialist MD. Since Geronova started only selling this through Amazon I've bought it here and not had any problems with the quality. I believe based on my long experience with both Geronova and Amazon that the problems people have had with unsealed bottles etc are most likely due to tampering by someone at the Amazon storage/shipping end of things. I've had such problems with other things I've ordered through Amazon. Just my opinion but BE SURE YOU ARE ORDERING FROM GERONOVA AND NOT ANOTHER VENDOR selling through amazon since the latter means even more opportunity for bottles to be tampered with or not actually being the genuine product. Yes it's more expensive than Alpha Lipoic Acid, but the research shows that it's up to 40 times more bioavailable. My experience is consistent with this. As for not dissolving as one person stated, R-Lipoic Acid doesn't dissolve in water. I purchased the 100% R-Lipoic Acid powder from Geronova when it was available and it just floated on top of water and would not dissolve. So I don't know what the person making the complaint might have been using before which dissolved. Just guessing it might have been Alpha Lipoic Acid. If you look at published research it indicates that Lipoic Acid and Biotin compete for the same receptors in the body. If you take any form of Lipoic Acid it's best to also take the Biotin (Vitamin B7) but the Biotin should be taken at a different time of day than the Lipoic Acid. The research also indicates that in order to get the highest levels in your brain, you should take the whole dose of Lipoic Acid at once on an empty stomach at least 30 minutes before eating anything else. (Don't take it in divided doses throughout the day.) I don't know if that's the most effective dosing schedule for other indications such as peripheral neuropathy. I'd say look at the research.

Seems to be a very quality product.

Easy daily dosage.I have more feeling not perfect but happy to have more

It's pricey and I don't have the equipment to test it to verify the label claim. I'm curious if any outside lab can test the significantly cheaper brands to see if the price is justified.

R factor as the only ingredient that appears to do what is required. Always ensure that you use the best ingredients.